Cardiovascular disease
In general, dose selection for an elderly patient should be cautious, usually starting at the low
photosensitivity. patients. The total daily dosage for pediatric patients may be calculated on the basis of body
Cyproheptadine Hydrochloride (500 mg),Cyproheptadine Hydrochloride (500 mg) * USP procures materials worldwide and most foreign materials do not undergo a fundamental change during the packaging process at USP that would substantially transform the item resulting in a country of origin change from the foreign origin to the United States. Target: 5-HT2 ReceptorCyproheptadine is a serotonin antagonist and a histamine H2 blocker used as antipruritic, appetite stimulant, antiallergic, and for the post-gastrectomy dumping syndrome, etc. Canada residents can call a provincial poison control center. Also, atropine-like signs and symptoms (dry-mouth; fixed, dilated
Cyproheptadine hydrochloride USP is a white to slightly yellowish crystalline solid, with a molecular weight of 350.89, which is soluble in water, freely soluble in methanol, sparingly soluble in ethanol, soluble in chloroform, and practically insoluble in ether. Cyproheptadine is a combined serotonin and histamine antagonist used in the treatment of allergic symptoms, for appetite stimulation, and off-label in the treatment of serotonin syndrome.. Generic Name Cyproheptadine DrugBank Accession Number DB00434 Background. FDA Safety Recalls, It is the sesquihydrate of 4-(5H-dibenzo[a,d]cyclohepten-5-ylidene)-1- methylpiperidine hydrochloride. is not allergic to the active substance or any of the excipients. evidence of impaired fertility or harm to the fetus due to cyproheptadine. Cyproheptadine is a prescription drug and can only be obtained from a veterinarian or by prescription from a veterinarian. No detectable amounts of unchanged drug were present in the urine of patients on chronic 12 to 20 mg daily doses. established. Patients). drug, taking into account the importance of the drug to the mother (see CONTRAINDICATIONS). This drug can often cause excitement in young children instead of drowsiness. Ø·ÙØ¨ Ø§ÙØ¨ØØ« Ù
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ØØªÙ٠داخ٠اÙÙØªØ§Ø¨ â ØµÙØØ© 318(Translated from Spanish: Effecto de la cyproheptadine sobre el peso corporal.) Bol. Hosp. S. Juan (Santiago), 14:342â346, 1969. . Idelshon, F.: Experience with cyproheptadine hydrochloride as a non-hormonal anabolic. Drug interactions may change how your medications work or increase your risk for serious side effects. Ø·ÙØ¨ Ø§ÙØ¨ØØ« Ù
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ØØªÙ٠داخ٠اÙÙØªØ§Ø¨ â ØµÙØØ© 1523... PHARMACIA AND UPJOHN 2MG N18173 001 CYCRIMINE HYDROCHLORIDE TABLET; ORAL PAGITANE LILLY 1.25MG N08951 001 2.5MG N08951 002 CYPROHEPTADINE HYDROCHLORIDE SYRUP; ORAL CYPROHEPTADINE HYDROCHLORIDE HALSEY 2MG/5ML N89199 001 Jul 03, ... Secara umum, berikut ini adalah dosis cyproheptadine untuk dalam pengobatan reaksi alergi yang dibagi bersadarkan usia pasien: Dewasa: Dosis awal 4 mg, 3-4 kali sehari. Dosage and frequency of administration are dependent on age, clinical response and
View Labeling Archives, An occasional patient may require as much as 32 mg a day for adequate relief. Cyproheptadine, sold under the brand name Periactin among others, is a first-generation antihistamine with additional anticholinergic, antiserotonergic, and local anesthetic properties. Cyproheptadine hydrochloride. It is consumed orally and has excellent protein binding capacity of 96% to 99%. It is can help stop runny nose, watery eyes, and itchy rash. It is not known if Cyproheptadine is safe and effective in children younger than 2 years. (See package circulars for physostigmine products.). Elimination is diminished in renal insufficiency. Get medical help right away if you have any very serious side effects, including: seizures. Hypotension, palpitation, tachycardia, extrasystoles, anaphylactic shock. Cyproheptadine is a first-generation antihistamine similar to diphenhydramine with the ability to penetrate the blood-brain barrier, and therefore, imposing a sedative effect. Ask your pharmacist about using those products safely. bottle. Biological Activity for Cyproheptadine hydrochloride. Files, All Mapping shown to be fetotoxic in rats when given by intraperitoneal injection in doses four times the maximum
3 There are no published studies evaluating cyproheptadine in insomnia; however, efficacy is inferred from studies evaluating diphenhydramine. Do not flush medications down the toilet or pour them into a drain unless instructed to do so. Nevertheless, because the studies in humans cannot rule out the possibility of harm, cyproheptadine should be used during pregnancy only if clearly needed. Monoamine oxidase inhibitor therapy (See DRUG INTERACTIONS.). PHARMACIST: Dispense in a well-closed container as defined in the USP, with a child-resistant closure (as required). Cyproheptadine (Periactin) is a first generation antihistamine traditionally used for allergic rhinitis, hives, and appetite stimulation.. Cyproheptadine acts on diverse pathways (more described below) and anticholinergic, antiserotonergic, and local anesthetic. If patient is unable to vomit, perform gastric lavage followed by activated charcoal. Cyproheptadine is an antihistamine used to relieve allergy symptoms such as watery eyes, runny nose, itching eyes /nose, sneezing, hives, and itching. Do not store in the bathroom. The total daily dose for adults should not exceed 0.5 mg/kg/day. Call your doctor for medical advice about side effects. Tell your doctor or pharmacist if you are taking other products that cause drowsiness such as opioid pain or cough relievers (such as codeine, hydrocodone), alcohol, marijuana (cannabis), drugs for sleep or anxiety (such as alprazolam, lorazepam, zolpidem), muscle relaxants (such as carisoprodol, cyclobenzaprine), or other antihistamines (such as cetirizine, diphenhydramine). Ask your doctor or pharmacist about using this product safely. antihistamines. Vasopressors may be used to treat hypotension. Before taking cyproheptadine, tell your doctor or pharmacist if you are allergic to it; or if you have any other allergies. Tablets have functional scoring. Citations, CONTRAINDICATIONS, Newborn or Premature Infants, WARNINGS, Activities Requiring Mental Alertness, Report Adverse Also, atropine-like signs and symptoms (dry mouth; fixed, dilated pupils; flushing, etc.) Cyproheptadine is used to treat sneezing, runny nose, itching, red or watery eyes, and other symptoms of seasonal allergies (hay fever). Cyproheptadine has an atropine-like action and, therefore, should be used with caution in patients with: Antihistamines may diminish mental alertness; conversely, particularly, in the young child, they may occasionally produce excitation. - Mechanism of Action & Protocol. Cyproheptadine hydrochloride is a 5-HT2A receptor antagonist, with antidepressant and antiserotonergic effects. (see CONTRAINDICATIONS, Newborn Or Premature Infants, and WARNINGS, Pediatric
Clinical studies of Cyproheptadine HCl tablets did not include sufficient numbers of
excreted in human milk, and because of the potential for serious adverse reactions in nursing infants
The dose is not to exceed 16 mg a day. Safety Information about Cyproheptadine hydrochloride (CAS NO.969-33-5): Hazard Codes: Xn: Risk Statements about Cyproheptadine hydrochloride (CAS NO.969-33-5): R22: Harmful if swallowed. A healthcare professional should be consulted before taking any drug, changing any diet or commencing or discontinuing any course of treatment. Ø·ÙØ¨ Ø§ÙØ¨ØØ« Ù
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ØØªÙ٠داخ٠اÙÙØªØ§Ø¨ â ØµÙØØ© 4852017. http://m. pdr.net/drug-summary/Cyproheptadine-Hydrochloride-Syrupcyproheptadine-hydrochloride-2646 Mahoney JS, Engebretson JC, Cook KF, et al. Spasticity experience domains in persons with spinal cord injury. cyproheptadine and difenoxin hcl both increase sedation. Application: Cyproheptadine hydrochloride is a non-selective 5-HT2 antagonist. Liquid products may contain alcohol and/or sugar. Cyproheptadine hydrochloride has antiplatelet and thromboprotective activities. Things to remember when you fill your prescription. Fatigue, chills, headache, increased appetite/weight gain. Make sure laboratory personnel and all your doctors know you use this drug. This medicine is used to treat allergy symptoms. Ø·ÙØ¨ Ø§ÙØ¨ØØ« Ù
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ØØªÙ٠داخ٠اÙÙØªØ§Ø¨ â ØµÙØØ© 211published: 14 July 2020 doi: 10.3389/fchem.2020.00575 Sensitive Immunochromatographic Assay Using Highly Luminescent Quantum Dot Nanobeads as Tracer for the Detection of Cyproheptadine Hydrochloride in Animal-Derived Food Pan Li1â , ... Cyproheptadine hydrochloride syrup is indicated in treatment of acute and chronic allergies such as dermatitis, eczema, mild and local allergic reactions to insect bites, hay fever, seasonal rhinitis, allergic conjuctivitis due to inhalant allergens and foods, urticaria, angioneurotic oedema, anogenital pruritus of chickenpox. and prematures in particular, antihistamine therapy is contraindicated in nursing mothers. It is a sedating antihistamine with antimuscarinic and calcium-channel blocking actions.It is used (particularly as the hydrochloride sesquihydrate) for the relief of . Ø·ÙØ¨ Ø§ÙØ¨ØØ« Ù
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ØØªÙ٠داخ٠اÙÙØªØ§Ø¨ â ØµÙØØ© 466... sodium Codeine phosphate Colchicine Colestipol hydrochloride Co-trimoxazole Cromolyn sodium Cyanocobalamin Cyclizine hydrochloride Cyclophosphamide Cyproheptadine hydrochloride Danazol Dapsone Dexamethasone Dextromethorphan Diazepam ... Use Caution/Monitor. This document does not contain all possible drug interactions. This medicine is used to treat allergy symptoms. It is well-absorbed orally and has a wide margin of safety. See additional information. 20 mg a day, with the majority of patients requiring 12 to 16 mg a day. Ø·ÙØ¨ Ø§ÙØ¨ØØ« Ù
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ØØªÙ٠داخ٠اÙÙØªØ§Ø¨ â ØµÙØØ© dlxxxiN008951 CYPROHEPTADINE HYDROCHLORIDE CYPROHEPTADINE HYDROCHLORIDE A089021 A087001 A089199 CYPROHEPTADINE HYDROCHLORIDE A086165 A087405 A086808 A088232 A070962 N013157 N018173 N008951 A086833 N013220 A088798 A087685 A089057 A086737 ... —It is well known that cyproheptadine hydrochloride (an antihistamine with serotonin-antagonistic activity) has an appetite-stimulating effect and promotes weight gain. If you miss a dose, take it as soon as you remember. Take your next dose at the regular time. It was patented in 1959 and came into medical use in 1961. The dosage is based on your age, medical condition, and response to treatment. metabolite found in human urine has been identified as a quaternary ammonium glucuronide conjugate of
Clinical Trials, Inhibitory effects of cyclobenzaprine, amitriptyline, and cyproheptadine . Antihistamines are more likely to cause dizziness, sedation, and hypotension in elderly patients. Allergic rhinitis (inflammation of the nasal passages) Golden State Medical Supply. confusion, restlessness, excitation, nervousness, tremor, irritability, insomnia, paresthesias, neuritis,
At least 40% of the administered radioactivity was excreted in the urine. For more information, ask your doctor or pharmacist. Caution is advised if you have diabetes, liver disease, or any other condition that requires you to limit/avoid these substances in your diet. Cyproheptadine is an antihistamine that reduces the effects of natural chemical histamine in the body. Cyproheptadine is used as an appetite stimulant in cats, but this effect does not appear to occur in dogs. requiring mental alertness and motor coordination, such as driving a car or operating machinery. Increased intraocular pressure
This medicine is used to treat allergy symptoms. Dosis maksimal 32 mg per hari. acute manifestations have been controlled. Cyproheptadine is an antihistamine that also has anti-serotonin activity. Serotonin is an important chemical messenger of the brain. 50488-5002-1, Cyproheptadine hydrochloride USP is a white to slightly yellowish crystalline solid, with a molecular weight of 350.89, which is soluble in water, freely soluble in methanol, sparingly soluble in ethanol, soluble in chloroform, and practically insoluble in ether. Ø·ÙØ¨ Ø§ÙØ¨ØØ« Ù
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ØØªÙ٠داخ٠اÙÙØªØ§Ø¨The internal filling solution was 10-3 M cyproheptadine hydrochloride of pH 5.0 (acetate buffer solution). The dinonylnaphthalenesulfonic acid in the PVC membrane was converted to ion-pair complex by soaking the sensor in cyproheptadine ... as well as gastrointestinal symptoms may occur. Inactive ingredients include: lactose monohydrate, magnesium stearate, microcrystalline cellulose, and sodium starch glycolate. Vasopressors may be used to treat hypotension. doses (10-4M) were cytotoxic. © 2005 - 2021 WebMD LLC. Cyproheptadine did not have any mutagenic effect in the Ames microbial mutagen test; concentrations of above 500 mcg/ plate inhibited bacterial growth. Ø·ÙØ¨ Ø§ÙØ¨ØØ« Ù
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ØØªÙ٠داخ٠اÙÙØªØ§Ø¨ â ØµÙØØ© 473( Journal abstract modified ) 078931 Benady , D. R. Child Guidance Clinic , The Shirehall , Shrewsbury , Shropshire , England Cyproheptadine hydrochloride ( Periactin ) and anorexia nervosa : a case report . Method: Studies of any design exploring the efficacy of CY as an appetite stimulant in all age groups and populations were included. Supplemental Information: This is classified as a Dangerous Good for transport and may be subject to additional shipping charges. Cyproheptadine is an antihistamine that reduces the effects of natural chemical histamine in the body. It is can help stop runny nose, watery eyes, and itchy rash. Cyproheptadine is a potent competitive antagonist of both serotonin and histamine receptors. Ø·ÙØ¨ Ø§ÙØ¨ØØ« Ù
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ØØªÙ٠داخ٠اÙÙØªØ§Ø¨ â ØµÙØØ© dccxxvii... CYCLOPENTOLATE HYDROCHLORIDE CYCLOPHOSPHAMIDE, CYCLOPHOSPHAMIDE CYCLOSPORINE, CYCLOSPORINE CYKLOKAPRON, TRANEXAMIC ACID CYMBALTA, DULOXETINE HYDROCHLORIDE CYPROHEPTADINE HYDROCHLORIDE, CYPROHEPTADINE HYDROCHLORIDE CYPROHEPTADINE ... CYPROHEPTADINE is a antihistamine. drugs a-z list
Cyproheptadine hydrochloride is indicated for the treatment of Perennial and seasonal allergic rhinitis; Vasomotor rhinitis; Allergic conjunctivitis due to inhalant allergens and foods; Mild, uncomplicated allergic skin manifestations of urticaria and angioedema; Amelioration of allergic reactions to blood or plasma; Cold urticaria; Dermatographism; As therapy for anaphylactic reactions . Because of the higher risk of antihistamines for infants generally and for newborns
Failure to thrive (FTT) impairs the expected normal physical growth of children. Keep all medications away from children and pets. HCl in normal subjects, given as tablets, 2-20% of the radioactivity was excreted in the stools. The lowest GoodRx price for the most common version of cyproheptadine is around $6.90, 75% off the average retail price of $28.43. Cyproheptadine hydrochloride Chemical Structure CAS NO. MAO inhibitors prolong and intensify the anticholinergic effects of
This medication may interfere with certain laboratory tests (including allergy skin testing, metyrapone test), possibly causing false test results. Cyproheptadine HCl USP, is an antihistaminic and antiserotonergic agent. Do not double the dose to catch up. Patients should be warned about engaging in activities requiring mental alertness and motor coordination, such as driving a car or operating machinery. Allergic manifestation of rash and edema, excessive perspiration, urticaria,
(current), cyproheptadine hydrochloride 4 MG Oral Tablet. from cyproheptadine, a decision should be made whether to discontinue nursing or to discontinue the
Cyprohepdaine HCl, is an antihistaminic and antiserotonergic agent. Hypersensitivity to cyproheptadine and other drugs of similar chemical structure. Acute labyrinthitis, blurred vision, diplopia, vertigo, tinnitus. R36/37/38: Irritating to eyes, respiratory system and skin. Ø·ÙØ¨ Ø§ÙØ¨ØØ« Ù
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ØØªÙ٠داخ٠اÙÙØªØ§Ø¨ â ØµÙØØ© 262For instance, hydroxyzine hydrochloride is particularly effective when administered to a patient with dermographism (13) or histamineinduced pruritus while cyproheptadine hydrochloride (Periactin) works best for cold urticaria (14). cyproheptadine and dimenhydrinate both increase sedation. Dryness of nose and throat, thickening of bronchial secretions, tightness of chest and wheezing, nasal stuffiness. Store at room temperature away from light and moisture. Before having surgery, tell your doctor or dentist about all the products you use (including prescription drugs, nonprescription drugs, and herbal products). home
Hemolytic anemia, leukopenia, agranulocytosis, thrombocytopenia. 2 Cyproheptadine hydrochloride boosts your appetite levels by blocking the action of serotonin receptors which are responsible for appetite levels in the body. These medications are not usually taken together. Precautions against aspiration must be taken especially in infants and children. Cyproheptadine Hydrochloride Oral solution What is this medicine? Objective: A systematic review identifying the use of cyproheptadine (CY) as an appetite stimulant was completed. Typically this medication is used only after a child is very comfortable having no symptoms of reflux ( such as vomiting, gagging, choking), as well has constipation managed ( stooling 1-2 times per day pudding . end of the dosing range, reflecting the greater frequency of decreased hepatic, renal, or cardiac
Two studies in pregnant women, however, have not shown that cyproheptadine increases the risk of abnormalities when administered during the first, second and third trimesters of pregnancy. Cyprohephtadine is used in the treatment of allergic conditions including:. Ø·ÙØ¨ Ø§ÙØ¨ØØ« Ù
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ØØªÙ٠داخ٠اÙÙØªØ§Ø¨ â ØµÙØØ© 238Cyproheptadine hydrochloride sesquihydrate GENERAL Cyproheptadine is a synthetic methylpiperidine derivative with antihistaminic (H1-blocking) and anti-serotoninergic properties. This agent exhibits anticholinergic and sedative ... Ø·ÙØ¨ Ø§ÙØ¨ØØ« Ù
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ØØªÙ٠داخ٠اÙÙØªØ§Ø¨ â ØµÙØØ© dxxviii... HYDROCHLORIDE TABLET; ORAL PAGITANE LILLY 1.25MG N008951 001 2.5MG N008951 002 CYPROHEPTADINE HYDROCHLORIDE SYRUP; ORAL CYPROHEPTADINE HYDROCHLORIDE HALSEY 2MG/5ML A089199 001 Jul 03, 1986 MORTON GROVE 2MG/5ML A087001 001 Nov 04, ... It is suggested that dosage be initiated with 4 mg (1 tablet) three times a day and adjusted according to the size and response of the patient. The therapeutic range is 4 to
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ØØªÙ٠داخ٠اÙÙØªØ§Ø¨ â ØµÙØØ© 224Pharmacology and Mechanism of Action Cyproheptadine is a phenothiazine with antihistamine and antiserotonin properties. ... Cyproheptadine has been used to treat head shaking in horses. ... 224 Cyproheptadine Hydrochloride. Safety Statements about Cyproheptadine hydrochloride (CAS NO.969-33-5): The dose is not to exceed 16 mg a day. Do not increase your dose or take this medication more often than directed. Antihistamine overdosage reactions may vary from central nervous system depression to stimulation especially in pediatric patients. US residents can call their local poison control center at 1-800-222-1222. Histamine can produce symptoms of sneezing, itching, watery eyes, and runny nose. Cyproheptadine hydrochloride can be used for the research of thromboembolic disorders. cyproheptadine increases the risk of abnormalities when administered during the first, second and third
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ØØªÙ٠داخ٠اÙÙØªØ§Ø¨ â ØµÙØØ© 245CYPROHEPTADINE HYDROCHLORIDE 245. Cyproheptadine. hydrochloride. CLINICAL USE Antihistamine: DOSE IN PATIENTS UNDERGOING RENAL REPLACEMENT THERAPIES # Symptomatic relief of allergy such as hay CAPD Unlikely to be dialysed. Drowsiness was a common . Antihistamines may have additive effects with alcohol and other CNS depressants,
Safety and effectiveness in pediatric patients below the age of two have not been
), allergies, pre-existing diseases, and current health conditions (e.g. RxNorm, CYPROHEPTADINE is a antihistamine. The oral LD of Cyproheptadine is 123 mg/kg, and 295 mg/kg in the mouse and rat, respectively. If vomiting has not occurred spontaneously, the patient should be induced to vomit with syrup of ipecac. does not suffer with severe renal impairment. pregnancy, upcoming surgery, etc. Cyproheptadine is used to treat sneezing, runny nose, itching, red or watery eyes, and other symptoms of seasonal allergies (hay fever). Only about 34% of the stool radioactivity was unchanged drug, corresponding to less than 5.7% of the dose. Synonyms for cyproheptadine hydrochloride in Free Thesaurus. Consult your doctor before breast-feeding. Also SETD7/9 inhibitor (IC 50 = 1 μ M). Cyproheptadine has an atropine-like action and, therefore, should be used with caution in
Do not drive, use machinery, or do anything that needs alertness or clear vision until you can do it safely. Inhibits growth of MCF7 xenografts in mice. This medicine may be used for other purposes; ask your health care provider or pharmacist if you have questions. Copyright © 2021 by RxList Inc. RxList does not provide medical advice, diagnosis or treatment. hypnotics, sedatives, tranquilizers, antianxiety agents. Cypropheptadine (or periactin) is an antihistamine (similar to benadryl), which frequently has the side effects of increase in hunger. Cyproheptadine hydrochloride sesquihydrate is an antihistamine and is an antagonist of serotonin and histamine2. Do not start, stop, or change the dosage of any medicines without your doctor's approval. CYPROHEPTADINE HYDROCHLORIDE TABLETS, USP. Store at 20° to 25°C (68° to 77°F) excursion permitted to 15° to 30°C (59° to 86°F) [See USP Controlled Room Temperature]. trimesters of pregnancy. To relieve dry mouth, suck (sugarless) hard candy or ice chips, chew (sugarless) gum, drink water, or use a saliva substitute. Ø·ÙØ¨ Ø§ÙØ¨ØØ« Ù
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ØØªÙ٠داخ٠اÙÙØªØ§Ø¨ â ØµÙØØ© dlxxi... 1995 CYCLOTHIAZIDE TABLET; ORAL ANHYDRON LILLY 2MG N013157 002 FLUIDIL PHARMACIA AND UPJOHN 2MG N018173 001 CYCRIMINE HYDROCHLORIDE TABLET; ORAL PAGITANE LILLY 1.25MG N008951 001 2.5MG N008951 002 CYPROHEPTADINE HYDROCHLORIDE SYRUP; ... Ø·ÙØ¨ Ø§ÙØ¨ØØ« Ù
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ØØªÙ٠داخ٠اÙÙØªØ§Ø¨ â ØµÙØØ© 156PERCODAN - DEMI RX PERITRATE TABLET , ORAL 07337 ENDO PRODS INC CAFFEINE , 32MG OXYCODONE HYDROCHLORIDE , 2.250MG ... ORAL * 12649 MERCK SHARP AND DOHME INTERNATL CYPROHEPTADINE HYDROCHLORIDE , 4MG PERIACTIN HCL TABLET , ORAL 16747 ...